Cologuard has become a popular colon cancer screening option. Indeed, it has many advantages over the traditional colonoscopy. Refer to the list below. No prep! No prep! No time off of work. No driver needed. No procedural risk. Done at home. No driving or other restrictions afterwards.\ Much less expensive. Did I mention there is no prep:? Wow, Cologuard sounds like it will be hard to beat. Not so fast! Cologuard is a sophisticated stool DNA test that detects altered DNA as well as microscopic blood in the stool. Studies have shown that it detects over 90% of colon cancers. Keep in mind that the overwhelming number of patients undergoing colonoscopy do not have cancer so that this statistic doesn’t apply to them. How does this stool DNA test perform with respect to colon polyps, which are the target lesions during colonoscopy? Cologuard detects only 42% of larger precancerous polyps which seems to me to be rather lackluster performance. ...
Editor’s Note: For 16 years, I've published weekly essays here on Blogspot, which will continue. I’ve now begun publishing my work on a new blogging platform, Substack, and I hope you’ll join me there. Please enter your email address at this link to receive my posts directly to your inbox. I did hospital work for 30 years until I accepted a position almost 7 years ago as an employed staff gastroenterologist at a rather renown Cleveland-based medical institution. I have been enjoying the luxury of practicing outpatient gastroenterology exclusively, freed from the rigors of hospital work and weekend and on-call responsibilities. It’s a job description that I feel I have earned after 3 decades of hard labor, but I was lucky that this position was available to me. During my hospital career, I estimate that I have placed a hundred or so feeding tubes, primarily in elderly patients, many of whom were demented. (In retrospect, gastroenterologists like me were p...